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Oxygen transport: association and dissociation & Factors that affect hemoglobin's saturation with O2

By: HWC, Views: 6591

• The production of oxyhemoglobin can be illustrated through the following reaction: 02 + Hb-H --) Hb-02 + H+ • This equation represents the binding of oxygen to the iron ions in heme groups in hemoglobin molecules. • Oxygen binding or loading occurs at the lungs • The dissociatio...

Oxygen - hemoglobin dissociation curve & Hemoglobin's affinity with oxygen - acidity

By: HWC, Views: 7280

• The partial pressure of oxygen is a primary factor influencing the degree of saturation of hemoglobin. • The Po2 determines the number of oxygen molecules that can bind or dissociate from hemoglobin. • Blood in vessels coming from the lungs is very high in Po2 so saturation is high. ...

Hemoglobin's affinity with oxygen - carbon dioxide, temperature and bisphosphoglycerate (BPG)

By: HWC, Views: 6775

• The carbon dioxide gas is temporarily converted to carbonic acid in red blood cells by the enzyme carbonic anhydrase, and then further converted to hydrogen and bicarbonate ions. • The result of increased carbon dioxide is decreased pH causing the Bohr effect. • Elevated carbon dioxid...

Oxygen transport - methods and oxyhemoglobin

By: HWC, Views: 6412

• The blood is the medium used for gas transport throughout the body. • Oxygen is only available in the lungs. Because the partial pressure of oxygen is higher in the alveoli than in the blood, oxygen diffuses into the blood and is transported to systemic cells. • At the tissues the par...

How Hemoglobin Picks Up and Delivers Oxygen

By: HWC, Views: 5914

All of the cells in our bodies require oxygen (02) for survival and must release carbon dioxide (CO2) as a waste product. The respiratory and circulatory systems work together as delivery systems for these gases. The lungs exchange these gases between the environment and the bloodstream. The bloo...

Introduction to Sickle Cell Anemia

By: Administrator, Views: 10079

Sickle cell anemia (sickle cell disease) is a disorder of the blood caused by an inherited abnormal hemoglobin (the oxygen-carrying protein within the red blood cells). The abnormal hemoglobin causes distorted (sickled appearing under a microscope) red blood cells.

Hydrogen bonds - role in the body

By: HWC, Views: 7003

A hydrogen bond is the electromagnetic attraction between polar molecules in which hydrogen is bound to a larger atom, such as oxygen or nitrogen. This is not a sharing of electrons, as in a covalent bond. Instead, this is an attraction between the positive and negative poles of charged atoms. ...

Red Blood Cells - Erythropoietin (EPO)

By: HWC, Views: 6662

• The endocrine system maintains many body conditions within normal limits with feedback loops. Each endocrine feedback loop maintains homeostasis using the following components: • Stimulus - a change in a body condition. • Production cell - an endocrine cell that produces a hormone aft...

Exercise and cardiac output & Definition of stroke volume

By: HWC, Views: 6608

▪ Cardiac output: • Maintains blood flow throughout the body. • Measure of blood volume ejected from the heart over a given time. • Determined by multiplying heart rate by stroke volume (CO = SV x HR). • Heart rate: Number of beats/min. • Stroke volume: Amount of blood eject...